The role of ocular dendritic cells in uveitis

W Lin, T Liu, B Wang, H Bi - Immunology letters, 2019 - Elsevier
Dendritic cells (DCs) act as a bridge between innate and adoptive immunity. They are widely
distributed in various tissues and organs. Resident ocular DCs are found in the peripheral
margins and juxtapapillary areas of the retina, usually in an immature state. During
inflammation, DCs are activated and participate in the development of uveitis, an ocular
inflammatory disease. Herein, the characteristics and status of DCs in uveitis, the possible
factors affecting the status of DCs, and the clinical methods for detecting the DCs in patients …